WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=20; E=3.75; R=5.33; rawP=2.36e-10; adjP=3.61e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000232810 NA TNF tumor necrosis factor 7124 ENSG00000232810
2  ENSG00000184113 NA CLDN5 claudin 5 7122 ENSG00000184113
3  ENSG00000128917 NA DLL4 delta-like 4 (Drosophila) 54567 ENSG00000128917
4  ENSG00000168758 NA SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 54910 ENSG00000168758
5  ENSG00000111859 NA NEDD9 neural precursor cell expressed, developmentally down-regulated 9 4739 ENSG00000111859
6  ENSG00000100060 NA MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 4242 ENSG00000100060
7  ENSG00000068028 NA RASSF1 Ras association (RalGDS/AF-6) domain family member 1 11186 ENSG00000068028
8  ENSG00000161940 NA BCL6B B-cell CLL/lymphoma 6, member B 255877 ENSG00000161940
9  ENSG00000143079 NA CTTNBP2NL CTTNBP2 N-terminal like 55917 ENSG00000143079
10  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
11  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001
12  ENSG00000176597 NA B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 84002 ENSG00000176597
13  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
14  ENSG00000136826 NA KLF4 Kruppel-like factor 4 (gut) 9314 ENSG00000136826
15  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
16  ENSG00000174951 NA FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2523 ENSG00000174951
17  ENSG00000184937 NA WT1 Wilms tumor 1 7490 ENSG00000184937
18  ENSG00000118515 NA SGK1 serum/glucocorticoid regulated kinase 1 6446 ENSG00000118515
19  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
20  ENSG00000164736 NA SOX17 SRY (sex determining region Y)-box 17 64321 ENSG00000164736


Database:Transcription Target       Name:hsa_RYTTCCTG_V$ETS2_B       ID:DB_ID:2415
C=1074; O=11; E=1.39; R=7.89; rawP=1.16e-07; adjP=8.87e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
2  ENSG00000184113 NA CLDN5 claudin 5 7122 ENSG00000184113
3  ENSG00000178878 NA APOLD1 apolipoprotein L domain containing 1 81575 ENSG00000178878
4  ENSG00000128917 NA DLL4 delta-like 4 (Drosophila) 54567 ENSG00000128917
5  ENSG00000168758 NA SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 54910 ENSG00000168758
6  ENSG00000111859 NA NEDD9 neural precursor cell expressed, developmentally down-regulated 9 4739 ENSG00000111859
7  ENSG00000144655 NA CSRNP1 cysteine-serine-rich nuclear protein 1 64651 ENSG00000144655
8  ENSG00000118515 NA SGK1 serum/glucocorticoid regulated kinase 1 6446 ENSG00000118515
9  ENSG00000068028 NA RASSF1 Ras association (RalGDS/AF-6) domain family member 1 11186 ENSG00000068028
10  ENSG00000143537 NA ADAM15 ADAM metallopeptidase domain 15 8751 ENSG00000143537
11  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:Transcription Target       Name:hsa_RGAGGAARY_V$PU1_Q6       ID:DB_ID:2447
C=495; O=8; E=0.64; R=12.45; rawP=2.50e-07; adjP=1.28e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000232810 NA TNF tumor necrosis factor 7124 ENSG00000232810
2  ENSG00000143537 NA ADAM15 ADAM metallopeptidase domain 15 8751 ENSG00000143537
3  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
4  ENSG00000108622 NA ICAM2 intercellular adhesion molecule 2 3384 ENSG00000108622
5  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
6  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
7  ENSG00000019102 NA VSIG2 V-set and immunoglobulin domain containing 2 23584 ENSG00000019102
8  ENSG00000133574 NA GIMAP4 GTPase, IMAP family member 4 55303 ENSG00000133574


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=15; E=3.18; R=4.72; rawP=3.51e-07; adjP=1.34e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
2  ENSG00000184113 NA CLDN5 claudin 5 7122 ENSG00000184113
3  ENSG00000128917 NA DLL4 delta-like 4 (Drosophila) 54567 ENSG00000128917
4  ENSG00000198719 NA DLL1 delta-like 1 (Drosophila) 28514 ENSG00000198719
5  ENSG00000168758 NA SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 54910 ENSG00000168758
6  ENSG00000136826 NA KLF4 Kruppel-like factor 4 (gut) 9314 ENSG00000136826
7  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
8  ENSG00000144655 NA CSRNP1 cysteine-serine-rich nuclear protein 1 64651 ENSG00000144655
9  ENSG00000100060 NA MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 4242 ENSG00000100060
10  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
11  ENSG00000184937 NA WT1 Wilms tumor 1 7490 ENSG00000184937
12  ENSG00000170989 NA S1PR1 sphingosine-1-phosphate receptor 1 1901 ENSG00000170989
13  ENSG00000164736 NA SOX17 SRY (sex determining region Y)-box 17 64321 ENSG00000164736
14  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
15  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:Transcription Target       Name:hsa_V$ETS1_B       ID:DB_ID:2057
C=255; O=6; E=0.33; R=18.12; rawP=1.02e-06; adjP=3.12e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143537 NA ADAM15 ADAM metallopeptidase domain 15 8751 ENSG00000143537
2  ENSG00000178878 NA APOLD1 apolipoprotein L domain containing 1 81575 ENSG00000178878
3  ENSG00000168758 NA SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 54910 ENSG00000168758
4  ENSG00000133574 NA GIMAP4 GTPase, IMAP family member 4 55303 ENSG00000133574
5  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001
6  ENSG00000144655 NA CSRNP1 cysteine-serine-rich nuclear protein 1 64651 ENSG00000144655


Database:Transcription Target       Name:hsa_TGTTTGY_V$HNF3_Q6       ID:DB_ID:2423
C=733; O=8; E=0.95; R=8.41; rawP=4.64e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000118515 NA SGK1 serum/glucocorticoid regulated kinase 1 6446 ENSG00000118515
2  ENSG00000143537 NA ADAM15 ADAM metallopeptidase domain 15 8751 ENSG00000143537
3  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
4  ENSG00000168758 NA SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 54910 ENSG00000168758
5  ENSG00000164736 NA SOX17 SRY (sex determining region Y)-box 17 64321 ENSG00000164736
6  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
7  ENSG00000019102 NA VSIG2 V-set and immunoglobulin domain containing 2 23584 ENSG00000019102
8  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:Transcription Target       Name:hsa_GGGAGGRR_V$MAZ_Q6       ID:DB_ID:2430
C=2250; O=13; E=2.92; R=4.45; rawP=4.70e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000128917 NA DLL4 delta-like 4 (Drosophila) 54567 ENSG00000128917
2  ENSG00000168758 NA SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 54910 ENSG00000168758
3  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
4  ENSG00000006210 NA CX3CL1 chemokine (C-X3-C motif) ligand 1 6376 ENSG00000006210
5  ENSG00000144655 NA CSRNP1 cysteine-serine-rich nuclear protein 1 64651 ENSG00000144655
6  ENSG00000163788 NA SNRK SNF related kinase 54861 ENSG00000163788
7  ENSG00000184937 NA WT1 Wilms tumor 1 7490 ENSG00000184937
8  ENSG00000143537 NA ADAM15 ADAM metallopeptidase domain 15 8751 ENSG00000143537
9  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
10  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
11  ENSG00000164736 NA SOX17 SRY (sex determining region Y)-box 17 64321 ENSG00000164736
12  ENSG00000170989 NA S1PR1 sphingosine-1-phosphate receptor 1 1901 ENSG00000170989
13  ENSG00000019102 NA VSIG2 V-set and immunoglobulin domain containing 2 23584 ENSG00000019102


Database:Transcription Target       Name:hsa_V$PU1_Q6       ID:DB_ID:2196
C=230; O=5; E=0.30; R=16.74; rawP=1.26e-05; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143537 NA ADAM15 ADAM metallopeptidase domain 15 8751 ENSG00000143537
2  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
3  ENSG00000108622 NA ICAM2 intercellular adhesion molecule 2 3384 ENSG00000108622
4  ENSG00000006210 NA CX3CL1 chemokine (C-X3-C motif) ligand 1 6376 ENSG00000006210
5  ENSG00000133574 NA GIMAP4 GTPase, IMAP family member 4 55303 ENSG00000133574


Database:Transcription Target       Name:hsa_V$SP1_Q4_01       ID:DB_ID:2308
C=252; O=5; E=0.33; R=15.28; rawP=1.96e-05; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000161940 NA BCL6B B-cell CLL/lymphoma 6, member B 255877 ENSG00000161940
2  ENSG00000127528 NA KLF2 Kruppel-like factor 2 (lung) 10365 ENSG00000127528
3  ENSG00000143079 NA CTTNBP2NL CTTNBP2 N-terminal like 55917 ENSG00000143079
4  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
5  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:Transcription Target       Name:hsa_V$SP1_Q6       ID:DB_ID:1986
C=251; O=5; E=0.33; R=15.34; rawP=1.92e-05; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000161940 NA BCL6B B-cell CLL/lymphoma 6, member B 255877 ENSG00000161940
2  ENSG00000127528 NA KLF2 Kruppel-like factor 2 (lung) 10365 ENSG00000127528
3  ENSG00000143079 NA CTTNBP2NL CTTNBP2 N-terminal like 55917 ENSG00000143079
4  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
5  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).